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pubblicata il 19.07.2016

Prakash, Gaurav, et al. "Assessment of bilateral pupillary centroid characteristics at varying illuminations and post‐photopic flash response using an automated pupillometer." Clinical and Experimental Optometry 99.6 (2016): 535-543.


Author information: Department of Cornea and Refractive Surgery, NMC Eye Care, New Medical Center Specialty Hospital, Abu Dhabi, United Arab Emirates. drgauravprakash@gmail.com. 2 Department of Cornea and Refractive Surgery, NMC Eye Care, New Medical Center Specialty Hospital, Abu Dhabi, United Arab Emirates

BACKGROUND:

The aim was to assess the symmetry and magnitude of illumination-dependent centroid shift and of post-photic flash re-dilatation response for normal pupils.

METHODS:

This cross-sectional, observational, inter-eye comparative study was performed at a specialty hospital. Fifty eyes (25 volunteers) without any ocular abnormality underwent pupillometry for scotopic (0.4 lux), mesopic (4.0 lux), photopic conditions (40 lux) and for rate of pupillary re-dilatation after a photopic flash (500 lux) with an inbuilt pupillometer on a Scheimpflug device (Sirius, CSO, Italy). Main outcome measures were pupillary centroids at different illuminations and time-dependent pupil diameters after a photic flash response.

RESULTS:

The mean pupil size for scotopic, photopic and mesopic pupils were significantly different (p < 0.001, ANOVA) for right and left eyes, analysed separately. The post-photic flash re-dilatation diameter was measured at zero, one, two, four, six, eight and 10 seconds after the flash. The mean diameters at given times post-photic flash were comparable in fellow eyes (p > 0.5, t-test) and highly correlated (r ≥ 0.8, p < 0.05 at all timed comparisons). The mean pupil diameter followed a time-dependent cubic function for both the right and left eyes. Speed was also governed by a time-dependent cubic function for both the right and the left eyes.

CONCLUSIONS:

Fellow eye symmetry is seen in illumination-governed centroid shifts and the post-flash re-dilatation response. The pupil dilates back briskly with a time-dependent cubic function, which is similar for fellow eyes in normal patients.

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